WebMar 1, 2024 · Docetaxel is an antineoplastic agent belonging to the taxoid family. It is prepared by semisynthesis beginning with a precursor extracted from the renewable … WebEuropean Medicines Agency -

Premedication for prophylaxis of taxane hypersensitivity …

Web1 to 21. Day 1. Dexamethasone. 8 mg (PO) with or after food for 3 doses (twelve hours, three hours and one hour prior to docetaxel administration) DOCEtaxel. 75 mg/m 2 (IV infusion) … WebPatients were randomized to receive ADT plus 75 mg/m 2 of docetaxel every 21 days for a maximum of 6 cycles or ADT alone. The researchers did not allow intermittent ADT. They required standard dexamethasone premedication, although daily prednisone was optional. Between July 28, 2006, and November 21, 2012, the authors enrolled 790 men in the study. dr whetstone palo alto

Study Supports Low-Dose Dexamethasone as Premedication for …

Web9. Chouhan et al. Single premedication dose of dexamethasone 20mg IV before DOCEtaxel administration. J Oncol Pharm Practice 2010;17(3): 155–159 10. Rogers ES et al. Efficacy … WebPS80 and CrEL are suggested to contribute to a variety of adverse events related to the infusion of docetaxel and paclitaxel, including peripheral neuropathy, fluid retention, taxane related cardiovascular adverse events, and severe hypersensitivity reaction during intravenous infusions. 14–18 Corticosteroids are prescribed as premedication prior to the … Web• May be substituted for paclitaxel or docetaxel if the patient has experienced hypersensitivity reactions despite premedication or the patient has contraindications to standard hypersensitivity premedication; OR • Used for recurrent, advanced, or metastatic disease (excluding locoregional recurrence or comfort first coupons